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. 2010 Dec 9;5(12):e14275. doi: 10.1371/journal.pone.0014275

Figure 6. Hepatotoxic changes in HepG2-A16 cells after treatment with high dose primaquine for 9 days.

Figure 6

Culturing HepG2-A16 cells with high concentrations of primaquine (10 µg/mL) induced hepatotoxic changes. P: Parasite; White arrows: Dense bodies in cytoplasm; E: Empty spaces due to focal cell loss in the cell culture well.