Table 4. Geometric Mean HI Titer against the Seasonal and the 2009 A/H1N1 Influenza Virus in Two Groups of Mice with Different Vaccination Procedures#.
Day 0 | Day 21 | Day 35 | ||||
GMT (95% CI) | Seasonal | 2009 A/H1N1 | Seasonal | 2009 A/H1N1 | Seasonal | 2009 A/H1N1 |
Group A (Nā=ā10) | 5 (5-5) | 5 (5-5) | 5 (5-5) | 5 (5-5) | 5 (5-5) | 149 (104-215) |
Group B (Nā=ā10) | 5 (5-5) | 5 (5-5) | 160 (115-223)** | 5 (5-5) | 160 (115-223)** | 197 (155-250) |
Group A: mice immunized with PBS (control) on day 0 and the 2009 A/H1N1 influenza vaccine on day 21; Group B: mice immunized with the 2008-09 trivalent seasonal influenza vaccine on day 0 and the 2009 A/H1N1 influenza vaccine on day 21.
Seasonal: geometric mean HI titer against the 2008-09 trivalent seasonal influenza vaccine; 2009 A/H1N1: geometric mean HI titer against the 2009 A/H1N1 pandemic influenza vaccine.
**(p<0.001) represents the statistical differences between Group A and Group B (two-way Student's t-test).