Table 1. Sensitivity, Specificity, and Positive Predictive Value (PPV) Associated with IgG to MsgC1 Cutpoints at Each Time Interval Comparing PcP Cases and Controls.
Time | Samples in Cases | Samples in Controls | MsgC1 Cutpoint | Sensitivity | Specificity | PPV |
Baseline | 180 | 107 | 23 | 57.2 | 61.7 | 71.5 |
1–2 weeks | 59 | 27 | 25 | 61.0 | 70.4 | 81.8 |
3–4 weeks | 41 | 11 | 40.5 | 63.4 | 100 | 100 |
5–6 weeks | 32 | 16 | 20.5 | 53.1 | 56.3 | 70.8 |
Note: We included 110 individual PcP cases and 63 individual controls in this study. Since some patients had their first specimen drawn at the time of hospital admission, but others had it drawn a day after admission, we defined baseline specimen to be specimen drawn on the day of hospital admission (day 0) or the following day after admission (day 1). Some subjects had specimens on both days and this resulted into 180 specimens for cases and 107 sample for controls.