Table 2. Sensitivity, Specificity, and Positive Predictive Value (PPV) Associated with IgM to MsgC1 Cutpoints at Each Time Interval Comparing PcP Cases and Controls.
Time | Samples in Cases | Samples in Control | MsgC1 Cutpoint | Sensitivity | Specificity | PPV |
Baseline | 77 | 31 | 23.49 | 59.7 | 61.3 | 79.3 |
1–2 weeks | 77 | 36 | 20.39 | 64.9 | 69.4 | 82.0 |
3–4 weeks | 32 | 19 | 20.36 | 74.6 | 73.7 | 89.8 |
Note: We had 110 individual PcP cases and 63 individual controls in this study. Since some patients had their first specimen drawn at the time of hospital admission, but others had it drawn a day after admission, we defined baseline specimen to be specimen drawn on the day of hospital admission (day 0) or the following day after admission (day 1). Some subjects had specimens on both days and this resulted into 77 specimens for cases and 31 sample for controls. There are different numbers of specimens for IgG and IgM in each group because some subjects was not enough for both IgG and IgM antibodies to be tested.