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. 2010 Dec 9;5(12):e15133. doi: 10.1371/journal.pone.0015133

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Wilson et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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For all ALS patients (A), survival was significantly longer (p<0.014) in patients with high cystatin C levels (n = 21) than in patients with low cystatin C levels (n = 11). For patients with limb onset ALS (B), the same trend was observed, but with a larger survival difference (p<0.010) between patients with high (n = 13) and low (n = 10) cystatin C levels.