Table 1. Clinical characteristics of all study participants.
ALS (n = 44) | All Disease Controls (n = 25) | Mimic Disease Controls (n = 9) | Healthy controls (n = 35) | |
Sex (male/female) | 31/13 | 13/12 | 7/2 | 13/22 |
Age at first draw ± SD (years) | 54.8±13.5 | 47.9±15.4 | 57.2±11.8 | 46.8±15.6 |
Relevant subgroups | 35 limb onset, 5 bulbar onset, 4 mixed/other onset | 9 ALS mimics, 6 MS, 10 other | 2 PLS, 2 CIDP, 2 PMA, 1 SA, 1 small fiber neuropathy, 1 idiopathic sensorimotor polyneuropathy | NA |
MS = multiple sclerosis; PLS = primary lateral sclerosis; CIDP = chronic inflammatory demyelinating polyneuropathy; PMA = progressive muscular atrophy; SA = spinocerebellar ataxia; NA = not applicable.