Table 1. FMDV isolates used in this study.
| Serotype | Virus strain | Topotype | Passage history | Country of origin | GenBank Accession No. |
| SAT1 | KNP/196/91* | 1 | PK1RS1 | South Africa | AF283429 |
| SAT1 | KNP/148/91 | 1 | PK1 RS5 | South Africa | GU194495 |
| SAT1 | ZIM/HV/3/90 | 1 | BTY1 RS3 | Zimbabwe | GU194496 |
| SAT1 | ZIM/GN/13/90 | 1 | BTY1 PK1 RS3 | Zimbabwe | GU194497 |
| SAT1 | KNP/41/95 | 1 | PK1 RS4 | South Africa | GU194498 |
| SAT1 | SAR/9/81* | 1 | Epithelium | South Africa | DQ009715 |
| SAT1 | NAM/307/98 | 2 | PK1 RS4 | Namibia | AY770519 |
| SAT1 | ZIM/6/94 | 2 | PK1 RS3 | Zimbabwe | GU194500 |
| SAT1 | TAN/37/99 | 3 | BTY1 RS4 | Tanzania | DQ009718 |
| SAT1 | ZAM/2/93 | 3 | PK1 RS3 | Zambia | DQ009719 |
| SAT1 | ZIM/25/90 | 3 | BTY2 RS4 | Zimbabwe | GU194499 |
| SAT1 | MOZ/3/02 | 3 | PK1 RS5 | Mozambique | DQ009720 |
| SAT1 | KEN/5/98 | 3 | BTY1 RS3 | Kenya | DQ009721 |
| SAT1 | UGA/3/99 | 4 | BTY1 RS4 | Uganda | DQ009722 |
| SAT1 | UGA/1/97 | 5 | PK1 RS4 | Uganda | AY043300 |
| SAT1 | NIG/5/81* | 7 | BTY2 RS2 | Nigeria | DQ009723 |
| SAT1 | SUD/3/76 | 7 | BTY1 RS3 | Sudan | DQ009725 |
| SAT1 | NIG/15/75 | 8 | BTY1 RS3 | Nigeria | DQ009724 |
| SAT1 | NIG/8/76 | 8 | BTY1 RS5 | Nigeria | GU194503 |
| SAT1 | NIG/6/76 | 8 | BTY1 RS5 | Nigeria | GU194502 |
| SAT2 | KNP/19/89* | I | BHK4 | South Africa | DQ009735 |
| SAT2 | KNP/2/89 | I | CFK2 RS2 BHK4 | South Africa | GU194488 |
| SAT2 | KNP/51/93 | I | PK1 RS6 | South Africa | GU194489 |
| SAT2 | ZIM/1/88 | I | CFK1 RS4 | Zimbabwe | GU194491 |
| SAT2 | SAR/16/83 | I | B1 BHK8 | South Africa | DQ009734 |
| SAT2 | ZIM/14/90 | II | BTY1 RS3 | Zimbabwe | DQ009728 |
| SAT2 | ZIM/17/91 | II | BTY2 RS4 | Zimbabwe | DQ009727 |
| SAT2 | ZIM/GN/10/91 | II | BTY2 PK1 RS3 | Zimbabwe | GU194493 |
| SAT2 | RHO/1/48 | II | BTY2 RS2 | Zambia | AJ251475 |
| SAT2 | ZIM/7/83* | II | B1 BHK5 B1 | Zimbabwe | AF540910 |
| SAT2 | ZIM/34/90 | II | BTY3 RS4 | Zimbabwe | GU194490 |
| SAT2 | ZIM/8/94 | II | BTY1 RS3 | Zimbabwe | GU194492 |
| SAT2 | KEN/8/99 | IV | BTY2 RS4 | Kenya | AY254730 |
| SAT2 | GHA/8/91 | V | BTY1 RS3 | Ghana | DQ009732 |
| SAT2 | SEN/5/75 | V | BTY1 RS1 BHK5 | Liberia | DQ009738 |
| SAT2 | SEN/7/83 | VI | CK1 RS1 | Senegal | DQ009733 |
| SAT2 | SAU/6/00 | VII | BTY1 RS1 | Saudi Arabia | AY297948 |
| SAT2 | ERI/12/89* | VII | BTY2 PK1 RS5 | Eritrea | GU194494 |
| SAT2 | RWA/2/01* | VIII | PK1 RS1 | Rwanda | DQ009730 |
| SAT2 | ANG/4/74 | XI | BTY3 RS3 | Angola | DQ009736 |
| SAT2 | UGA/2/02 | XII | PK1 RS1 | Uganda | DQ009731 |
| SAT2 | ZAI/1/74 | XII | BTY2 RS4 | Zaire | DQ009737 |
Protective strains are starred.