Table 2. New ADPRT toxin features.

Name	Length	Domainsa	Secretionb	Psoluble c	Crystallizationd	Targete
Chelt	601	Ia (∼1–179, toxin); Ib(∼180–240); II (∼241–601, lectin-like)	SP (18|19)	0.141	Amenable	Gαs R201
Certhrax	476	I (∼1–241, PA binding); II (∼242–476, toxin)	0.706	0.519	High scoring	Asn, Gln or Cys?
Mav toxin	825	I (∼1–96, ESAT6); II (∼97–439, pore forming?); III (∼440–675, disordered); IV (∼675–825, toxin)	0.822	0.332	Recalcitrant	Arg?
EFV toxin	487	I (∼1–309, needle/pore forming?); II (∼310–487, toxin)	0.731	0.258	Recalcitrant	Arg?
TccC5	938	I (∼1–341, β-propeller); II (∼342–675, β-propeller); III (∼676–738, helical); IV (∼739–938, toxin)	0.936	0.599	Amenable	RhoA Q61
Vis toxin	249	I (1–249, toxin)	SP (18|19)	0.611	Amenable	Arg?

^aPredicted by DOMAC, Ginzu or sliding-window fold recognition.

^bSecretomeP scores >0.5 suggest secretion without specific signal peptide; “SP” indicates secretion signal peptide detected by SignalP.

^cProbability of solubility by PROSO.

^dParCrys crystallization propensity.

^eExpected target amino acid (refer to main text for more information).