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. Author manuscript; available in PMC: 2011 Jul 1.
Published in final edited form as: Expert Opin Biol Ther. 2010 Jul;10(7):1121–1130. doi: 10.1517/14712598.2010.493872
Drug name Bapineuzumab
Phase III
Indication Alzheimer’s disease
Pharmacology Humanized monoclonal IgG1 antibody against the β-amyloid (Aβ) N- terminus(Aβ1–5), based on the murine antibody 3D6 and intended to promote Aβ clearance from the brain
Route of administration Intravenous
Pivotal trials Phase II [1,53], Phase III (NCT00575055 and NCT00574132)