Table 1.
Cohort Demographic Differences
| Control N = 20 |
Depressed, Remitted N = 16 |
Depressed, Nonremitted N = 13 |
Test value, df |
P value | |
|---|---|---|---|---|---|
| Age (y) | 74.3 (4.4) | 66.4 (5.9) | 68.4 (7.2) | F 2,48 = 9.24 | 0.0004 |
| Sex, % Female (N) |
40.0 (8) | 62.5 (10) | 53.9 (7) | χ2 = 1.86, 1 df |
0.3951 |
| Age of initial depression onset (y) |
- | 50.1 (19.6) | 56.4 (14.9) | t = 0.95, 27 df |
0.3505 |
| Antidepressant use at follow-up, % (N) |
0 | 75.0 (12) | 84.6 (11) | χ2 = 0.40, 1 df |
0.5250 |
| MADRS, entry | 1.9 (2.1) | 25.1 (3.9) | 25.2 (4.4) | F 2,48 = 270.13 |
< 0.0001 |
| MADRS, 1 year | 0.9 (1.2) | 4.0 (2.2) | 14.6 (4.5) | F 2,48 = 101.48 |
< 0.0001 |
| MMSE | 28.9 (1.2) | 27.6 (2.2) | 28.4 (1.0) | F 2,48 = 3.20 | 0.0501 |
| CIRS | 5.7 (2.3) | 5.7 (2.5) | 6.9 (3.7) | F 2,48 = 0.93 | 0.4018 |
| Days between MRIscans |
455.9 (40.7) |
450.6 (116.2) | 450.8 (106.5) | F 2,48 = 0.02 | 0.9809 |
The comparison for antidepressant use only compared depressed cohorts, not the control cohort.