Figure 5.

Lymphatic reflux. (A) A closer view of the lymph vessel with lymph reflux in the asymptomatic arm of subject LA03 seen in Figure 4F (Video W3 for visualization). In this example, there appears to be insufficient valvular function allowing a portion of each forward moving packet to drain back from ROI 2 (red) to ROI 1 (blue) as illustrated in (B) a three-dimensional plot of fluorescent intensity as a function of time and distance. By following the intensity peaks, the direction of flow is determined. (C) Fluorescent intensity profiles at ROIs 1 and 2.