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. 2010 Dec 15;99(12):3916–3922. doi: 10.1016/j.bpj.2010.10.043

Table 1.

Parameters obtained from fits of ramp-force probability density distributions to the Bell-Evans model (Eq. 1)

Loading rate (pN/s) k0 (s−1) dtr (nm) Faverage (pN)
Myo1cIQ-tail-2% PtdIns(4,5)P2 dissociation
250 ± 29 9.4 ± 2.4 2.2 ± 0.35 5.6 ± 0.33
930 ± 120 11 ± 1.8 0.64 ± 0.051 16 ± 0.43
1800 ± 230 43 ± 9.6 0.61 ± 0.13 13 ± 0.89
Lipid extraction
1100 ± 130 12 ± 3.9(8.7 ± 3.7) 0.33 ± 0.083(0.45 ± 0.085) 27 ± 1.6

Errors are obtained from a bootstrap analysis.

Parameters from fits assuming that the rupture peaks are due to either a single bond or two independent bonds that fail simultaneously (Eq. 5). The fraction of single bonds is A = 0.6 ± 0.1.