Skip to main content
. 2010 Dec 14;1(5):e00284-10. doi: 10.1128/mBio.00284-10

TABLE 5 .

Effects of inhibitors on 14C-labeled amino acid uptake by the WT and ALZ42 strains

Strain and presence of added H2 14C-labeled amino acid uptake (cpm [103]/108 cells)a at:
5 min 10 min
WT
 None 29.0 ± 2.0 31.0 ± 1.1
 CCCP 0.7 ± 0.5b 0.3 ± 0.2b
 Orthovanadate 14.8 ± 1.2b 18.7 ± 1.0b
ALZ42 (Hyb only)
 None 14.0 ± 1.6 18.2 ± 3.5
 CCCP 0.3 ± 0.1b 0.04 ± 0.07b
 Orthovanadate 5.5 ± 0.8b 9.5 ± 0.7b
a

 Values represent 14C-labeled amino acid uptake by 108 cells ± standard deviation (n = 4).

b

 Significantly lower uptake level than without inhibitor (P < 0.005 [Student’s t test]).