Figure 8. The basal levels of ATP at the ventral surface of the medulla can be blocked by gap junction hemichannel antagonists.

A, the effect of several agents on the ATP tone recorded following removal of ATP biosensors from the surface of the slice (indicated by double headed arrow for control case). B, summary statistics showing the effect of these antagonists on the magnitude of the resting ATP tone. Analysis suggests that the samples are not drawn from the same population (P = 0.029, Kruskal–Wallis test). The probabilities next to the bars indicate pairwise comparisons to the control.