. 2010 Aug 31;588(Pt 20):4017–4027. doi: 10.1113/jphysiol.2010.197814

Table 2.

Forearm and systemic haemodynamics for subjects in primary experimental protocol

		Baseline			Dose 1			Dose 2			Dose 3			Dose 4

		FBF	MAP	HR	FBF	MAP	HR	FBF	MAP	HR	FBF	MAP	HR	FBF	MAP	HR
ACh	Young	2.1 ± 0.3	86 ± 2	55 ± 1	6.7 ± 1.0	86 ± 2	57 ± 3	7.4 ± 1.0	86 ± 2	55 ± 2	9.6 ± 1.0	87 ± 2	55 ± 2	14.4 ± 1.9	86 ± 2	55 ± 2
	Young + AA	2.1 ± 0.2	89 ± 2	54 ± 2	6.3 ± 0.7	89 ± 2	54 ± 1	8.2 ± 1.0	89 ± 2	55 ± 2	10.1 ± 1.1	89 ± 2	54 ± 2	13.6 ± 1.5	89 ± 2	57 ± 2
	Older	1.9 ± 0.1	98 ± 2	56 ± 1	3.5 ± 0.4^*^†	99 ± 2	57 ± 1	4.6 ± 0.3^*^†	100 ± 2	58 ± 2	5.3 ± 0.6^*^†	99 ± 2	58 ± 2	6.3 ± 0.9^*^†	100 ± 2	58 ± 2
	Older + AA	1.9 ± 0.1	101 ± 2	56 ± 2	6.8 ± 1.1	102 ± 3	55 ± 2	7.7 ± 1.1	103 ± 2	57 ± 2	9.4 ± 1.2	103 ± 2	57 ± 2	12.2 ± 1.9	103 ± 2	57 ± 1
ATP	Young	2.1 ± 0.2	86 ± 2	53 ± 3	8.2 ± 1.0	87 ± 2	55 ± 2	11.6 ± 1.5	88 ± 2	56 ± 2	14.2 ± 1.7	87 ± 2	56 ± 2	15.7 ± 2.1	87 ± 2	55 ± 2
	Young + AA	2.0 ± 0.2	90 ± 2	54 ± 2	7.5 ± 1.0	91 ± 2	54 ± 2	10.1 ± 1.2	91 ± 2	55 ± 2	12.5 ± 1.9	90 ± 2	56 ± 1	15.1 ± 2.5	91 ± 2	57 ± 2
	Older	2.0 ± 0.2	98 ± 2	56 ± 1	7.9 ± 0.9	99 ± 2	57 ± 2	9.8 ± 1.0	98 ± 2	58 ± 2	11.6 ± 1.6	98 ± 2	58 ± 2	13.9 ± 1.7	98 ± 2	58 ± 2
	Older + AA	1.9 ± 0.1	100 ± 3	56 ± 2	8.1 ± 0.1	101 ± 3	56 ± 1	10.7 ± 1.4	102 ± 2	57 ± 2	12.9 ± 1.3	101 ± 2	58 ± 2	16.4 ± 1.7	102 ± 3	58 ± 2
SNP	Young	2.1 ± 0.3	86 ± 2	55 ± 2	8.2 ± 1.2	87 ± 2	56 ± 2	11.7 ± 1.4	85 ± 2	56 ± 2	17.7 ± 1.9	83 ± 2	61 ± 2	21.3 ± 2.1	82 ± 2	62 ± 2
	Young + AA	2.1 ± 0.2	89 ± 2	55 ± 2	8.4 ± 1.0	92 ± 2	56 ± 2	11.8 ± 1.3	90 ± 2	55 ± 2	17.9 ± 1.8	87 ± 2	57 ± 2	21.5 ± 2.0	85 ± 2	60 ± 2
	Older	1.8 ± 0.1	98 ± 3	57 ± 1	7.8 ± 0.5	99 ± 3	57 ± 1	11.1 ± 1.2	96 ± 3	58 ± 1	15.6 ± 1.2	94 ± 2	59 ± 2	19.4 ± 1.8	89 ± 2	61 ± 2
	Older + AA	2.0 ± 0.2	101 ± 3	56 ± 2	8.8 ± 1.1	103 ± 3	56 ± 2	12.0 ± 1.6	101 ± 2	57 ± 2	17.0 ± 1.6	96 ± 2	58 ± 2	20.6 ± 1.9	93 ± 2	61 ± 2

FBF, forearm blood flow (ml (100 ml)⁻¹ min⁻¹); MAP, mean arterial pressure (mmHg); HR, heart rate (beats min⁻¹)

P < 0.05 vs. young

^†

P < 0.05 vs. with AA; note, all absolute MAP values for older adults are significantly greater than young.