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. 2010 Mar 9;10(3):1871–1889. doi: 10.3390/s100301871

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© 2010 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland.

This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).

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Figure 10. — Cancer cell targeting and spectroscopic detection by using antibody-conjugated SERS nanoparticles. Preparation of targeted SERS nanoparticles by using a mixture of SH-PEG (thinly—polyethylene glycol) and a hetero-functional PEG (SH-PEG-COOH). Covalent conjugation of an EGFR-antibody (epidermal growth factor receptor) fragment occurs at the exposed terminal of the hetero-functional PEG. © 2010 Nature Publishing Group.