Table IV.II.
Association between sports/recreational physical activity and hormones stratified by menopausal status1: Means ± SE among a sample of 667 women with breast cancer.2
| Tertile 1 (< 2.6 METhr/wk) | Tertile 2 (2.6 – 13.2 METhr/wk) | Tertile 3 (≥ 13.3 METhr/wk) | P for trend | |
|---|---|---|---|---|
| Mean ± SE (n = 236) | Mean ± SE (n = 238) | Mean ± SE (n = 236) | ||
| C-Peptide (ng/mL) | ||||
| Premenopausal | 2.02 ± 0.13 | 1.91 ± 0.10 | 1.86 ± 0.09 | .33 |
| Postmenopausal | 2.40 ± 0.07 | 2.46 ± 0.07 | 2.27 ± 0.08 | .27 |
| Leptin (ng/mL) | ||||
| Premenopausal | 18.4 ± 1.8 | 21.6 ± 1.4 | 17.5 ± 1.3 | .68 |
| Postmenopausal | 27.3 ± 0.9 | 24.8 ± 0.9 | 25.0 ± 1.0 | .099 |
| IGF-1 (ng/mL) | ||||
| Premenopausal | 153.6 ± 9.3 | 160.7 ± 7.5 | 171.0 ± 6.8 | .14 |
| Postmenopausal | 123.6 ± 3.8 | 126.9 ± 3.8 | 126.8 ± 4.0 | .56 |
| IGFBP-3 (ug/mL) | ||||
| Premenopausal | 3.89 ±0.14 | 4.17 ± 0.12 | 4.26 ± 0.10b | .046 |
| Postmenopausal | 4.05 ±0.07 | 4.05 ± 0.07 | 4.08 ± 0.08 | .77 |
| IGF-I:IGFBP-3 (ng/mL) | ||||
| Premenopausal | 39.4 ± 2.0 | 39.3 ±1.6 | 40.2 ± 1.4 | .73 |
| Postmenopausal | 30.4 ± 0.8 | 31.5 ± 0.8 | 31.0 ± 0.8 | .60 |
1
Sample sizes for premenopausal women: Tertile 1: N = 31, Tertile 2: N = 45; Tertile 3: N = 58; postmenopausal women: Tertile 1: N = 189, Tertile 2: N = 176; Tertile 3: N = 168.
2
Adjusted for study site, age, ethnicity, education, disease stage, adjuvant treatment, tamoxifen use, type 2 diabetes, smoking status, and body mass index.
a
Tertile 2 significantly different from Tertile 1, p < .05.
b
Tertile 3 significantly different from Tertile 1, p < .05.
c
Tertile 3 significantly different from Tertile 2, p < .05.