Twelve-spin simulations of the PMPT and CRDSD experiments on the NAL single crystal. A) Varying the spinlock field on the 1H spinlock field for three different 15N spinlock fields (17.5, 33, and 50 kHz) at a MMHH mixing time of 20 msec. Note that for a 1H spinlock field of 0 kHz, this is the CRDSD experiment for a 17.5 kHz 15N spin-lock and the RFDSD experiment for larger 15N spin-locks. B) Build-up for the most optimal transfer efficiencies in panel A. For 15N spinlocks of 17.5, 33, and 50 kHz, the 1H spinlock field was maximal at 22.5, 40, and 55 kHz, respectively. C) Several mixing time build-up curves for different 1H spinlock fields when the 15N spinlock was set to 17.5 kHz.