Table 1.

Percentage inhibition of total cells, neutrophils and lymphocytes with RO5024118 in the bronchoalveolar lavage fluid of mice 24 h after exposure to lipopolysaccharide

% inhibition
RO5024118 (% w/v)	Total cells	Neutrophils	Lymphocytes
0.00003	10.1 ± 11.2	12.1 ± 11.6	29.8 ± 17.1
0.0001	19.1 ± 7.1	20.8 ± 8.1	38.4 ± 15.1
0.0003	41.6 ± 5.3	48.2 ± 5.9	41.6 ± 5.3
0.001	33.4 ± 5.4	40.7 ± 5.6	33.1 ± 8.6
0.003	37.1 ± 5.4	40.9 ± 6.5	66.4 ± 7.8
0.01	21.8 ± 6.0	23.5 ± 6.3	42.2 ± 11.2
0.03	15.4 ± 6.8	17.8 ± 6.6	44.0 ± 9.6
0.1	12.4 ± 5.8	15.9 ± 6.2	57.7 ± 7.5

Percentage inhibition calculated relative to vehicle. Data are mean ± SEM of five experiments.