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Percentage inhibition of cells with RO5024118 or dexamethasone in the airway of rats 24 h after exposure to porcine pancreatic elastase
| % inhibition | ||
|---|---|---|
| RO5024118 (% w/v) | Neutrophil | Total cells |
| 0.001 | 53.4 ± 7.6 | 27.8 ± 5.7 |
| 0.0003 | 85.6 ± 4.7 | 70.5 ± 5.1 |
| Dexamethasone (0.1%) | 15.7 ± 14.2 | 16.0 ± 11 |
Percentage inhibition calculated relative to vehicle. Data are mean ± SEM of four experiments.
