Table 2.
Contraction frequency
| Drugs | Control (contract per 5 min) | CPA 10–15 min | CPA + Mito drug 0–5 min | CPA + Mito drug 25–30 min | n |
|---|---|---|---|---|---|
| CPA + CCCP | 6.0 ± 1.5 | 10.8 ± 1.9a | 10.0 ± 2.2 | 8.6 ± 2.4 | 5 |
| CPA + rotenone | 6.4 ± 1.2 | 9.6 ± 0.8a | 7.6 ± 1.2 | 5.4 ± 2.2 | 5 |
| CPA + CGP37157 | 6.8 ± 1.2 | 10.2 ± 1.0a | 9.2 ± 1.1a | 6.0 ± 1.5 | 5 |
| CPA + kaempferol | 7.8 ± 1.8 | 10.1 ± 1.1 | 8.4 ± 1.0 | 6.8 ± 1.0 | 5 |
Values are mean ± SEM.
a
Significantly different from control, P < 0.05 (Student's two-tailed paired t-test).
CCCP, carbonylcyanide-3-chlorophenylhydrazone; CGP37157, 7-chloro-5-(2-chlorophenyl)-1,5-dihydro-4,1-benzothiazepin-2(3H)-one; CPA, cyclopiazonic acid; Mito, mitochondrial.