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. 2010 Nov;161(6):1414–1426. doi: 10.1111/j.1476-5381.2010.00976.x

Table 2.

Tonic block of WT NaV1.1 and R1648H channels

Tonic block of peak current Tonic block of persistent current
Log IC50 k Log IC50 k
WT NaV1.1 −3.06 ± 0.13 (871 µM) −0.84 ± 0.15 −4.27 ± 0.04 (53.7 µM) −0.83 ± 0.06
R1648H −3.31 ± 0.09 (490 µM) −1.00 ± 0.19 −4.52 ± 0.04 (30.2 µM) −1.00 ± 0.09