. Author manuscript; available in PMC: 2011 Sep 1.

Published in final edited form as: Gastroenterol Clin North Am. 2010 Sep;39(3):681–695. doi: 10.1016/j.gtc.2010.08.015

Table 2. Long-term effect of carvedilol on portal pressure in studies including at least 10 patients.

Study	Setting	n	Mean Dosage (mg/d)	Mean Decrease in HVPG (%)	Hemodynamic Responders (%)
Stanley 1999⁶⁰	Mixed	10	25	16	4 (40)
Banares 2002^a^,²⁴	Primary	24	31	19	13 (54)
Bruha 2006⁶¹	Mixed	36	25	^∼16	15 (42)
Total		70			32 (46)

Only comparative study with propranolol using a homogenous population of patients without a history of variceal hemorrhage and a baseline HVPG of 12 mm Hg or more. Mean decrease in HVPG with propranolol was 12% and rate of responders was 23% (see Table 1).