Table 2.

Standardized Terminology Dictionary mapping performance

Total Drug Concepts in Terminology Dictionary	16269
	PHARMetrics	GE
Unique Product Identifiers in reference file	22454	28501
Distinct annotation proportion	79.39% (17827)	69.79% (19892)
Drug References in Person data	718590080	231492741
Instance annotation proportion	97.91% (703584362)	96.68% (223799256)
Source drug annotations to Terminology Dictionary Drug Concepts Vioxx and rofecoxib	Vioxx Vioxx 12 mg Vioxx 12 mg/5 ml Vioxx 25 mg Vioxx 25 mg/5 ml Vioxx 50 mg	Vioxx Vioxx 12 mg Vioxx 12 mg/5 ml Vioxx 25 mg Vioxx 25 mg/5 ml Vioxx 50 mg Rofecoxib NOC Rofecoxib

Total Condition Concepts in Terminology Dictionary	20666
	PHARMetrics	GE
Unique ICD-9 codes in reference file	29630	14972
Distinct annotation proportion	75.41% (22345)	85.47% (12797)
Unmapped, unique ICD-9 E and V codes	12.01% (3559)	13.80% (2066)
Unmapped, unique invalid codes	12.58% (3726)	0.73% (109)
Condition references in Person data	3627194305	81693914
Instance annotation proportion	84.56% (3067136827)	84.11% (68713570)
ICD-9 E and V codes in Person data	15.28% (554089276)	15.78% (12894228)
Invalid codes in Person data	0.16% (5968202)	0.11% (86116)

	PHARMetrics	GE
Source ICD-9 annotations to Condition Terminology Dictionary Concept ‘Acute Myocardial Infarction‘ (AMI)	410 Acute Myocardial Infarction 4100# AMI Anterolateral Wall 4101# AMI Anterior Wall 4102# AMI Inferolateral Wall 4103# AMI Inferoposterior Wall 4104# AMI Inferior Wall 4105# AMI Lateral Wall 4106# AMI True Posterior Wall 4107# AMI Subendocardial 4108# Acute Myocardial Infarction NEC 4109# Acute Myocardial Infarction NOS	410 Acute Myocardial Infarction 410.0# AMI Anterolateral Wall 410.1# AMI Anterior Wall 410.2# AMI Inferolateral Wall 410.3# AMI Inferoposterior Wall 410.4# AMI Inferior Wall 410.5# AMI Lateral Wall 410.6# AMI True Posterior Wall 410.7# AMI Subendocardial 410.8# Acute Myocardial Infarction NEC 410.9# Acute Myocardial Infarction NOS