Table 3. Type I functional divergence between subfamilies of CYP3 in Actinopterygii.

	CYP3A c1	CYP3A c2	CYP3B	CYP3C	CYP3D
CYP3A c1		0.36±0.07	0.44±0.09	0.54±0.14	0.57±0.12
CYP3A c2	23.9*		0.57±0.05	0.43±0.08	0.50±0.07
CYP3B	25.0*	112.8*		0.20±0.11	0.43±0.08
CYP3C	14.6*	26.8*	3.6		0.62±0.14
CYP3D	23.5*	53.1*	25.6*	19.4*

Type I (θ_I) functional divergence (± standard error, upper right diagonal) and LRT values for significance (lower left diagonal) were estimated using DIVERGE. The significant tests at 1% cutoff are labeled with *.