Table 4. Analyses of the sequence data produced by Cohen et al. [11].

	Test
Sample	Collapsing	SCollapsing	AOC	GWWS	SGWWS
Sample 1	3.16E-3	1.29E-3	1.60E-3	1.96E-3	4.31E-4
Sample 2	0.03	0.01	0.02	0.02	0.02
Combined	1.23E-4	3.68E-5	3.90E-5	1.00E-4	5.86E-6

Notes: The candidate gene NPC1L1 was sequenced in two samples. The first sample (Sample 1) was comprised of 128 individuals with highest ratios of campesterol to lathosterol (Ca∶L ratio) and 128 individuals with lowest ratios from the Dallas Heart Study (DHS). A total number of 16 non-synonymous variants were analyzed, 13 of which are exclusive in cases and 3 exclusive in controls. The second sample (Sample 2) was comprised of the same number of individuals with the next highest and lowest Ca∶L ratios from the DHS. A total number of 12 non-synonymous variants were analyzed, 10 of which are exclusive in cases and 2 exclusive in controls. The combined sample was formed by combining the two samples together. See notes for table 1 for abbreviation detail.