Examples of lymphatic/blood vessel connections (arrows) classified as either direct contact (A, B, C) or direct alignment (D). Connections were defined as involving either a blind-ended lymphatic vessel (L) or blood capillary (c) or both. Apparent cases in which lymphatic and capillary blind ends are involved in directed growth toward each other (E) were not included in the connection analysis, but suggest the occurrence of common guidance signals. Scale bars, 20 μm (A, B, C, D), 100 μm (E).