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. 2008 Sep;159(3):546–554. doi: 10.1111/j.1365-2133.2008.08696.x

Fig 6.

Fig 6

Chemokine and chemokine receptor mRNA expression in the skin after topical exposure to oxazolone (OXA). Neutrophil-attracting chemokines CCL3/MIP-1α (a) and CXCL5/LIX (b) were significantly increased in OXA-treated Smad3−/− mice compared with wild-type (WT). The expression of Th2-associated chemokine CCL24 (eotaxin-2) was significantly increased in OXA-treated Smad3−/− mice compared with WT (d), while that of Th1-related chemokine CXCL10/IP10 was not (c). The expression of Th2-associated chemokine receptor CCR3 was significantly increased in Smad3−/− mice compared with WT (e). The results are shown as mean ± SEM. *P<0·05, **P<0·01, ***P<0·001.