Table 1.

Examples for regulons transferred between corynebacteria^a

	GlxR	LexA	RamB	McbR	DtxR
CG	99	20	47	46	64
					TP	FP
CD	35	9	27	11	25 of 63 (40%)	0
CE	104	14	22	26	18 of 27 (67%)	0
CJ	33	4	13	12	21 of 51 (41%)	0

^aThe table shows the number of known and predicted target genes for five transcription factors that are conserved among the species C. glutamicum (CG), C. diphtheriae (CD), C. efficiens (CE), and C. jeikeium (CJ). CG served as source organism, while CD, CE, and CJ are the target organisms. A combination of orthology detection, binding-site conservation and operon extension has been used for the inter-species transfer procedure(55). The DtxR regulons of CD, CE and CJ have been known in advance allowing us to judge the prediction performance, i.e. we may give numbers for true positives (TP) and false positives (FP).