. Author manuscript; available in PMC: 2010 Dec 12.

Published in final edited form as: Dev Biol. 2006 Apr 7;295(2):647–663. doi: 10.1016/j.ydbio.2006.03.051

Table 3.

Survival of embryos generated by Nog^+/−;Bmp4^+/− intercrosses

	Nog^+/+; Bmp4^+/−	Nog^+/−; Bmp4^+/+	Nog^+/−; Bmp4^+/−	Nog^−/−; Bmp4^+/+	Nog^−/−; Bmp4^+/−
E9–E17, n = 166	23	20	50	12	30
% Total	13.9	12	30	7.2	18.1
% Expected	12.5	12.5	25	6.3	12.5

Progeny of Nog^+/−; intercrosses were genotyped for Noggin and Bmp4 alleles. The “expected” percentage refers to the expected ratios predicted by independent segregation of unlinked loci. We saw no reduced representation of any of the genotypes listed here. Note that occurrence of genotypes above “Mendelian” expectation is predictable at these stages, in that Bmp4^−/− embryos very rarely survive this late (Winnier et al., 1995); their loss increases the observed frequencies of other genotypes.