Table 1.

Oligomerization domains present in PB and SG components. Oligomerization or dimerization domains relevant for foci formation were identified by deletion of distinct protein regions, or by fusion to reporter proteins. The oligomerization/dimerization domains are conserved in the species listed. The knockdown of molecules carrying the indicated aggregation domains affects foci formation in several cases. Similar putative dimerization/oligomerization domains present in additional PB components, including FMRP and CPEB, are present [46], [190], [194].

Protein	foci	Domain	Reference
Lsm4	PBs	C-terminal Q/N-rich (yeast)	[46], [47]
		C-terminal RG-rich (metazoans)
EDC3	PBs	C-terminal Yjef-N	[47], [48]
Gawky/GW182	PBs	Central Q-rich	[191]
Ge-1/Hedls/Varicose/EDC4	PBs	C-terminal Q/N-rich	[50], [51], [52], [53]
CCR4	PBs	N-terminal Q/N	[46]
Dhh1p	PBs	C-terminal Q/N	[46]
	SGs
Pop 2	PBs	C-terminal Q/N-rich	[46]
G3BP	SGs	N-terminal NTF2	[64]
TIA1/Pub1	SGs	C terminal Q/N rich	[18], [192]
	PBs
TIAR/Ngr1	SGs	C terminal Q/N rich	[18], [192]
	PBs
MNL51	SGs	C terminal Q-rich	[123]
Pumilio 2	SGs	N terminal Q-rich	[155]
Caprin	SGs	C-terminal Q-rich	[63]
TDP43	SGs	C-terminal PRD Q-rich	[156], [193]