Table I.
Protein binding constant (Kb) and number of binding sites (n) of MNPs in mannitol citrate buffer and PBS
Formulation | Mannitol Citrate Buffer | PBS | ||
---|---|---|---|---|
Kb (μg/μg) | n | Kb (μg/μg) | n | |
OE-20 MNPs | 12.2 × 10−2 | 1.3 | 5.6 × 10−2 | 1.2 |
OE-40 MNPs | 10.9 × 10−2 | 1.4 | 6.6 × 10−2 | 1.6 |
OE-80 MNPs | 7.2 × 10−2 | 1.3 | 5.8 × 10−2 | 1.4 |
Feridex IV | 11.1 × 10−2 | 1.3 | 16.7 × 10−2 | 1.9 |