. 2010 Nov 24;141(1):63–70. doi: 10.3945/jn.110.131888

TABLE 1.

Selected plasma amino acid concentrations in TPN- and PEN-fed pigs acutely i.g. infused with saline or arginine¹

Amino acid group	Feeding group	Arginine infusion rate, μmol⋅kg⁻¹⋅h⁻¹
Amino acid group	Feeding group	Saline²	50	100	200	400	800
		μmol/L
Arginine	TPN³	66 ± 7^a	124 ± 25^b	186 ± 35^b	283 ± 37^c	336 ± 105^c	404 ± 87^c
	PEN³	119 ± 6^a	nd⁴	252 ± 21^b	385 ± 30^c	685 ± 43^d	1394 ± 38^e
Ornithine⁵	TPN³	25 ± 3^a	34 ± 7^a	47 ± 7^b	71 ± 10^bc	82 ± 20^bc	113 ± 25^c
	PEN³	51 ± 5^a	nd	75 ± 7^b	108 ± 7^bc	178 ± 42^c	252 ± 12^d
Citrulline⁵	TPN	113 ± 17	118 ± 17	105 ± 8	125 ± 12	113 ± 17	111 ± 14
	PEN	142 ± 4	nd	152 ± 9	134 ± 9	153 ± 8	165 ± 12
Proline⁵	TPN	640 ± 100	574 ± 65	556 ± 37	610 ± 52	596 ± 61	677 ± 90
	PEN	493 ± 14^b	nd	352 ± 9^a	397 ± 33^a	387 ± 26^a	389 ± 25^a
Glutamine⁵	TPN	811 ± 125	619 ± 61	665 ± 42	645 ± 81	666 ± 92	628 ± 74
	PEN	447 ± 45	nd	392 ± 49	396 ± 45	410 ± 53	341 ± 34
Glutamate⁵	TPN	353 ± 82	302 ± 36	256 ± 39	334 ± 45	295 ± 35	310 ± 31
	PEN	234 ± 7	nd	188 ± 12	198 ± 19	190 ± 17	194 ± 16
Threonine	TPN	1161 ± 333	1151 ± 125	1188 ± 152	1196 ± 180	1121 ± 169	936 ± 198
	PEN	1089 ± 32	nd	989 ± 67	905 ± 87	986 ± 85	937 ± 82
Lysine	TPN	295 ± 85	318 ± 46	307 ± 33	305 ± 43	254 ± 41	261 ± 48
	PEN⁶	365 ± 10	nd	273 ± 27	237 ± 11	251 ± 22	250 ± 10

Means ± SEM, = 4–6 (TPN) or 9 (PEN) unless otherwise noted. Means in a row with superscripts without a common letter differ, P < 0.05.

Values for saline represent overall mean from each arginine dose level, = 24 (TPN) or 36 (PEN) unless otherwise noted.

Significant effect of treatment (TPN vs. PEN), < 0.05

⁴

nd, Not determined.

⁵

Significant arginine dose effect, linear < 0.01.

⁶

Significant arginine dose effect, linear < 0.05.