TABLE 2.

Growth, body composition, and organ weight of male and female offspring of rats fed CON or MD diet during the peri-conception period at 26 wk and the male offspring at 51 wk¹

	26 wk				51 wk
	Female		Male		Male		Significance2
	CON	MD	CON	MD	CON	MD	A3	S4	D	A × D3	S × D4
Body mass
At weaning, g	38.1 ± 0.95	38.3 ± 0.91	39.6 ± 0.92	40.0 ± 0.90	39.5 ± 1.05	40.2 ± 1.01	—	0.003	—	—	—
When killed, g	288 ± 7.6	292 ± 7.3	536 ± 7.2	560 ± 7.1	572 ± 11.2	598 ± 10.8	<0.001	<0.001	0.023	—	—
Body composition and organ weight
Fat, % body mass	11.4 ± 0.7	11.7 ± 0.6	13.4 ± 0.6	13.5 ± 0.6	18.9 ± 0.9	18.3 ± 0.9	<0.001	<0.001	—	—	—
Lean, % body mass	78.9 ± 0.6	78.4 ± 0.4	77.4 ± 0.9	77.2 ± 0.5	69.3 ± 0.9	69.1 ± 0.8	—	<0.001	—	—	—
Liver, g	8.1 ± 0.28	8.2 ± 0.27	15.6 ± 0.27	16.4 ± 0.27	17.2 ± 0.39	17.7 ± 0.38	<0.001	<0.001	0.077	—	0.077
Heart, g	0.86 ± 0.03	0.89 ± 0.03	1.34 ± 0.03	1.41 ± 0.03	1.34 ± 0.04	1.42 ± 0.03	—	<0.001	0.080	—	—
Kidney, g	0.92 ± 0.03	0.93 ± 0.03	1.63 ± 0.03	1.70 ± 0.03	1.59 ± 0.05	1.72 ± 0.05	—	<0.001	0.037	—	—
Soleus, mg	142 ± 4.9	149 ± 4.7	226 ± 4.6	237 ± 4.9	226 ± 5.4	238 ± 5.2	—	<0.001	0.023	—	—
Plantaris, mg	255 ± 7.9	263 ± 7.7	398 ± 7.6	435 ± 7.5	404 ± 9.6	419 ± 9.4	—	<0.001	< 0.001	—	0.017

¹Values are predicted means ± SEM, = 16 (1 pup /litter for each sex and age). Abbreviations: A, Age; S, Sex, and D, Dietary treatment.

²Where no value is shown, > 0.1.

³Age comparisons and A×D interactions pertain to male offspring only.

⁴Sex comparisons and S×D interactions pertain to 26-wk-old offspring only.