Cortiolimbic connectivity in major depression (N=15), healthy controls (N=15), bipolar disorder (N=11), bipolar mania (N=6), and bipolar depression (N=5). Post hoc t-tests results for significant differences with each of the mood disorder groups and healthy subjects as described in the text are denoted by *P<0.05, **P<0.01 and ***P<0.005. A. Pregenual anterior cingular cortex (ACC) and dorsomedial thalamus connectivity. B. Pregenual anterior cingular cortex (ACC) and amygdala connectivity. C. Pregenual anterior cingular cortex (ACC) and striatal connectivity.