Figure 6.
Quantification of cyclic guanosine monophosphate (cGMP) in lung homogenates after early concurrent treatment on Day 10 in room air–exposed (RA) and O2-exposed pups (O2) daily injected either with saline, apelin, Nω-nitro-l-arginine methyl ester (l-NAME), or a combination of apelin and l-NAME. Values are expressed as mean ± SEM (n = 10). *P < 0.05, ***P < 0.001 versus age-matched O2-exposed control pups. ΔP < 0.05, ΔΔΔP < 0.001 versus own room air-exposed control pups. $$$P < 0.001 versus apelin-treated O2 pups.