TABLE 1.
CHANGES IN THE EXPRESSION OF GENES (ΔGE) OF PROVEN OR POTENTIAL IMPORTANCE IN MALIGNANT PLEURAL EFFUSION PATHOGENESIS INDUCED IN LEWIS LUNG ADENOCARCINOMA CELLS BY 22 pM RECOMBINANT MOUSE IL-5*
| Gene Symbol | Microarray |
ELISA/CBA |
|||
|---|---|---|---|---|---|
| Gene Name | ΔGE | P | ΔGE | P | |
| Ccl2 | Chemokine (C-C motif) ligand 2 | 1.080 | 0.310 | 1.029 | 0.885 |
| Ccl12 | Chemokine (C-C motif) ligand 12 | 1.080 | 0.330 | 1.101 | 0.741 |
| Cxcl2 | Chemokine (C-X-C motif) ligand 2 | 1.020 | 0.800 | −1.090 | 0.720 |
| Ifng | Interferon-γ | 1.180 | 0.230 | 1.100 | 0.691 |
| Il6 | IL-6 | 1.020 | 0.660 | 1.011 | 0.978 |
| Il10 | IL-10 | −1.020 | 0.770 | 1.038 | 0.776 |
| Il12b | IL-12b | 1.090 | 0.260 | 1.243 | 0.489 |
| Tnf | Tumor necrosis factor | 1.180 | 0.230 | 1.171 | 0.515 |
| Vegfa | Vascular endothelial growth factor A | −1.020 | 0.650 | 1.046 | 0.852 |
Definition of Abbreviations: CBA = cytometric bead array; P = probability.
*
Determined at the RNA level by microarray and at the protein level by ELISA or CBA.