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. Author manuscript; available in PMC: 2011 Dec 15.
Published in final edited form as: Toxicol Appl Pharmacol. 2010 Oct 1;249(3):224–230. doi: 10.1016/j.taap.2010.09.019

Fig. 4.

Fig. 4

Effect of RA treatment on BPDE adduct levels in HepG2 cells. Levels of BPDE-dG and total DNA adducts in cells treated with 4 μM BP for 24 h then incubated another 24 h with DMSO were significantly lower compared to 48 h incubated with 4 μM BP (*P=0.02). After 24 h incubation with 4 μM BaP, the fresh medium was replaced with medium containing 1 μM RA for another 24 h. Total adduct levels were diminished significantly by RA compared to the medium with DMSO in second 24 h incubation (** p=0.032).