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. Author manuscript; available in PMC: 2011 May 1.
Published in final edited form as: Liver Transpl. 2010 May;16(5):600–610. doi: 10.1002/lt.22036

Figure 7. Activation of STAT1, STAT3 and JAK2 in LPS-stimulated hepatoma cells.

Figure 7

(A). Representative Western-blot analysis of phospho- and total STAT1 and phospho- and total STAT3. Within 1 h after treatment with LPS, STAT1 and STAT3 were robustly phosphorylated. Treatment with AG490, 2 h prior to LPS stimulation, significantly decreased both phospho-STAT1 and phospho-STAT3 expression in hepatoma cells (CRL1830) (*p < 0.05, n= 2/group). (B). Representative Western-blot analysis of JAK2 phosphorylation. Within 2 min after treatment with LPS, JAK2 became phosphorylated. Treatment with AG490, 2 h prior to LPS stimulation, significantly decreased phospho-JAK2 expression in hepatoma cells (CRL1830) (*p < 0.05, n= 2/group).