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Stability of total soluble lens proteins from a wild-type control mouse lens and from an αA-Y118D homozygous mouse lens at 60°C. Curve 1, 0.2 mg of total soluble protein obtained from a wild-type lens and heated to 60°C for 120 minutes in 0.5 mL; curve 2, 0.2 mg of total soluble proteins obtained from an αA-Y118D mouse lens and heated to 60°C in 0.5 mL; curve 3, same as curve 2 but with the addition of 50 microgram of recombinant αA-Y118D.
