Figure 7. Identification of residues exhibiting conformational exchange on the μs –ms timescale in PEP-19-bound apo C-CaM and Ca2+-C-CaM based on reduced spectral density mapping.
Values on the Y-axis are calculated by (J(0)i – J(0)avg)/SD. Residues with (J(0)i – J(0)avg)/SD >1.0 are considered to undergo significant chemical/conformational exchange. Asterisks indicate residues with extreme line broadening.