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. 2010 Dec 13;5(12):e14170. doi: 10.1371/journal.pone.0014170

Table 4. Antibiotics given for the treatment of SAB at any time during treatment, including early empirical treatment (N = 5781).

Antibiotics2 MRSA MSSA
UK (N = 105) Vietnam/Nepal (N = 14) UK (N = 402) Vietnam/Nepal (N = 57)
Flucloxacillin 19 (18%) 12 (86%) 340 (85%) 46 (81%)
Vancomycin 71 (68%) 10 (71%)3 88 (22%) 19 (33%)
Teicoplanin 41 (39%) 0 (0%) 61 (15%) 0 (0%)
Linezolid 15 (14%) 0 (0%) 12 (3%) 0 (0%)
Rifampin 22 (21%) 1 (7%) 62 (16%) 3 (5%)
Aminoglycoside 22 (21%) 2 (14%) 71 (18%) 11 (19%)
Fucidic acid 6 (6%) 0 (0%) 40 (10%) 0 (0%)
Clindamycin 3 (3%) 0 (0%) 43 (11%) 0 (0%)
1

Excludes 15/593 patients known to have been treated but information missing on antibiotics received (n = 10) or susceptibility to methicillin (n = 5, all received flucloxacillin).

2

Of 578 with information on antibiotics received, between 1–4 had missing information on whether they received an antibiotic. Antibiotics other than those listed were given to 81/578 (15%) patients. The most commonly used were a fluoroquinolone (n = 28, 5%) and doxycycline (n = 12, 2%). Daptomycin and tigecycline were used once.

3

The 4 patients not treated with vancomycin either died (n = 1) or were discharged (n = 3) within 24 hours of the positive blood culture.