Table 1. Proteins regulated through phosphorylation dependent degradation.

Protein	Species	Role	Degradation Time	Kinase(s)	No. of Sites*	Ref.
Sic1	S. cerevisiae	Cyclin-dependent kinase inhibitor	G1/S	Cln/Cdc28	9	[9]
Cdc6	S. cerevisiae	Replication initiator	G1/S	Clb/Cdc28	4	[67]
Cln2	S. cerevisiae	G1 cyclin	G1/S	Cdc28	7	[68]
Rum1	S. pombe	Cyclin-dependent kinase inhibitor	G1/S	Cdc2	2 (or 8?)	[56]
Cdc18	S. pombe	Replication initiator	G1/S	Cdc2	6	[69]
p27	Mammalia	Cyclin-dependent kinase inhibitor	G1/S	Cdk2, Src	4	[10]–[12]
Cyclin E	Mammalia	G1 cyclin	G1/S	Cdk2, Gsk3	4	[70], [71]
Cdc25A	Mammalia	Phosphatase (dephosphorylation of CDKs)	S	Chk1/2, ?	8	[72]
-catenin	Mammalia	Cadherin-associated protein	G2/M-G1	Gsk3, Cki	4	[50]
Runx1	Mammalia	Transcription factor (associated with M2 AML)	G2/M-G1	Cdk1	11	[57]
Emi1	Mammalia	Early mitotic inhibitor (inhibit APC)	M	Cdk1, Plk1	7	[73]
Gcn4	S. cerevisiae	Transcription activator	-	Srb10	5	[74]
		(biosynthesis of amino acids & purines)
Tec1	S. cerevisiae	Filamentous growth regulator	In response to	Fus3	2	[58]
			mating pheromone
HFR1	A. thaliana	Transcription factor in light regulation	In darkness	CKII	5	[59]
Bim	Mammalia	Apoptosis signaling	In response to	MAPK, JNK	4	[75]
			survival signals

*Phosphorylation sites shown to be involved in the regulation of the stability of the corresponding protein.