Figure 1. Three downstream sequences are conserved among MHC class I promoters.
The sequences +4 to +8 and +12 to +16 and +27/28 to +31/32 of the swine SLA class I gene, PD1, and the human HLA class genes, HLA-A, HLA-B and HLA-C were aligned. All four have conserved GAGA factor binding site and DPE consensus sequences.