Table 1. Microarray-based transcriptome analysis of testicular cells in adult wild type and VRK1-deficient mice.
Spermatogonia | p-value | Fold change | Regulation |
Stra8 | 0.031 | 2.79 | Down |
Dazl | 0.031 | 2.03 | Down |
Tacstd1 (Ep-CAM) | 0.042 | 2.18 | Down |
Crabp1 | 0.034 | 2.51 | Down |
Lin28a | 0.010 | 2.17 | Down |
Lin28b | 0.002 | 2.85 | Down |
Meiosis | p-value | Fold change | Regulation |
Ovol1 | 0.014 | 2.93 | Down |
Ccnb3 | 0.006 | 4.13 | Down |
Cpeb1 | 0.003 | 2.51 | Down |
Mei1 | 0.010 | 3.67 | Down |
Ccna1 | 0.037 | 2.07 | Down |
Sycp2 | 0.004 | 3.17 | Down |
Syce1 | 0.020 | 2.37 | Down |
Boll | 0.018 | 2.36 | Down |
Smc1b | 0.033 | 2.22 | Down |
Stag3 | 0.004 | 2.04 | Down |
Msh4 | 0.050 | 2.13 | Down |
Clgn | 0.037 | 2.05 | Down |
Suv39h2 | 0.036 | 2.03 | Down |
Spermatogenesis | p-value | Fold change | Regulation |
Tssk3 | 0.012 | 2.77 | Down |
Rnf17 | 0.023 | 2.26 | Down |
Mov10l1 | 0.017 | 2.25 | Down |
Ovol1 | 0.014 | 2.93 | Down |
Prok2 | 0.014 | 4.85 | Down |
Gal3st1 | 0.034 | 3.97 | Down |
Bmp8a | 0.006 | 2.06 | Down |
Bmp8b | 0.007 | 3.08 | Down |
Mtl5 | 0.013 | 2.43 | Down |
Dazl | 0.031 | 2.03 | Down |
Spag16 | 0.004 | 3.35 | Down |
Ccna1 | 0.037 | 2.07 | Down |
Hmga1 | 0.018 | 2.06 | Down |
Boll | 0.018 | 2.36 | Down |
Nlrp14 | 0.010 | 2.80 | Down |
Msh4 | 0.050 | 2.13 | Down |
Clgn | 0.037 | 2.05 | Down |
Hsf2bp | 0.002 | 3.53 | Down |
Dnmt3a | 0.010 | 2.04 | Down |
Jag2 | 0.006 | 2.45 | Down |
Gdnf | 0.027 | 2.25 | Up |
Differently expressed genes involved in spermatogonia, meiosis, and spermatogenesis in VRK1-deficient testes were listed.