Table 3:
Effect of dietary portfolios high and low in monounsaturated fatty acids (MUFA) on blood lipids, C-reactive protein and blood pressure in 24 study participants (data presented as means)
Variable | High-MUFA portfolio, n = 12 |
Low-MUFA portfolio, n = 12 |
Treatment difference* (95% CI) | p value | ||||
---|---|---|---|---|---|---|---|---|
Baseline |
Treatment |
Baseline |
Treatment |
|||||
Wk 4 | Wk 6 | Wk 8 | Wk 4 | Wk 6 | Wk 8 | |||
Body weight, kg | 82.10 | 81.85 | 81.33 | 78.70 | 79.00 | 77.47 | 0.31 (−0.51 to 0.78) | 0.19 |
Cholesterol, mmol/L | ||||||||
Total | 5.36 | 4.78 | 4.54 | 5.37 | 4.37 | 4.48 | 0.16 (−0.11 to 0.49) | 0.24 |
LDL | 3.61 | 2.97 | 2.81 | 3.49 | 2.67 | 2.73 | 0.08 (−0.13 to 0.33) | 0.43 |
HDL | 1.00 | 1.14 | 1.13 | 1.09 | 1.08 | 1.10 | 0.12 (0.05 to 0.21) | 0.003 |
Triglycerides | 1.64 | 1.49 | 1.33 | 1.72 | 1.37 | 1.41 | 0.00 (−0.26 to 0.22) | 0.92 |
Apolipoprotein, g/L | ||||||||
AI | 1.27 | 1.38 | 1.38 | 1.34 | 1.30 | 1.31 | 0.12 (0.05 to 0.18) | 0.001 |
B | 1.08 | 0.92 | 0.89 | 1.06 | 0.85 | 0.86 | 0.02 (−0.04 to 0.08) | 0.50 |
Ratios | ||||||||
Total:HDL cholesterol | 5.46 | 4.30 | 4.12 | 4.94 | 4.10 | 4.10 | −0.28 (−0.59 to −0.04) | 0.025 |
LDL:HDL cholesterol | 3.68 | 2.68 | 2.56 | 3.23 | 2.50 | 2.51 | −0.22 (−0.41 to −0.03) | 0.032 |
Apolipoprotein B:AI | 0.86 | 0.68 | 0.65 | 0.79 | 0.65 | 0.66 | −0.04 (−0.07 to 0.00) | 0.046 |
High-sensitivity C-reactive protein, mg/L | 1.87 | 0.89 | 0.81 | 1.50 | 1.50 | 1.85 | −1.27 (−1.76 to −0.39) | 0.003 |
Blood pressure, mm Hg | ||||||||
Systolic | 122 | 121 | 119 | 120 | 117 | 118 | 2 (−3 to 7) | 0.40 |
Diastolic | 75 | 73 | 72 | 71 | 69 | 71 | 1 (−2 to 4) | 0.45 |
Note: CI = confidence interval, HDL = high-density lipoprotein, LDL = low-density lipoprotein.
Difference in change over time between high- and low-MUFA groups, by repeated-measures analysis.