Table 2:

Parameters of intensive care unit (ICU) management and co-interventions

Variable	Hydrocortisone, mean (SD)*n = 39	Placebo, mean (SD)*n = 36	p value
Central venous pressure, mm Hg
Day 1	14.7 (6.5)	16.1 (5.9)	0.36
Day 3	14.1 (4.8)	13.9 (5.5)	0.89
Intra-abdominal pressure, mm Hg
Day 1	15.1 (3.5)	15.5 (5.8)	0.74
Day 3	13.7 (3.5)	17.2 (6.9)	0.01
Paracentesis, no. (%)	10 (26)	13 (36)	0.33
Venous oxygen saturation, %
Day 1	77.1 (11.1)	75.7 (9.8)	0.59
Day 3	77.7 (8.8)	75.0 (10.6)	0.28
Fluid intake, mL
Day 1	4126.6 (2554.0)	3967.9 (2583.4)	0.79
Day 3	2950.9 (1925.3)	3007.1 (1812.9)	0.90
Fluid output, mL
Day 1	1260.1 (1616.9)	1025.9 (1551.4)	0.52
Day 3	2192.3 (2484.1)	1638.9 (1783.6)	0.30
Packed red blood cell transfusion, units
Day 1	0.8 (1.7)	0.6 (1.0)	0.56
Day 3	0.4 (1.3)	0.2 (1.1)	0.46
Fresh frozen plasma, units
Day 1	2.7 (3.7)	1.9 (2.6)	0.26
Day 3	1.5 (3.0)	1.2 (2.2)	0.67
Platelets, units
Day 1	0.9 (2.6)	1.2 (2.6)	0.62
Day 3	1.0 (3.1)	0.5 (1.8)	0.43
Cryoprecipitate, units
Day 1	0.8 (2.7)	0.6 (2.3)	0.72
Day 3	0.3 (1.7)	0.0 (0.0)	0.28
Albumin 5%, mL
Day 1	179.5 (519.2)	111.2 (263.5)	0.47
Day 3	84.9 (218.3)	75.8 (169.2)	0.85
Albumin 20%, mL
Day 1	38.5 (104.2)	69.4 (109.1)	0.21
Day 3	51.4 (101.1)	79.7 (127.9)	0.31
Peak airway pressure, cm H2O
Day 1	28.4 (6.8)	28.5 (7.5)	0.95
Day 3	27.6 (5.4)	29.1 (7.1)	0.46
Mean airway pressure, cm H2O
Day 1	15.5 (5.5)	13.7 (5.9)	0.29
Day 3	14.2 (4.5)	14.3 (4.6)	0.96
PEEP, cm H2O
Day 1	8.9 (5.2)	7.3 (3.4)	0.18
Day 3	8.8 (3.0)	7.6 (3.1)	0.20
Renal replacement therapy, no. (%)	25 (64)	27 (75)	0.31

Note: PEEP = positive expiratory end pressure, SD = standard deviation.

^*Unless otherwise indicated.