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. Author manuscript; available in PMC: 2010 Dec 14.
Published in final edited form as: J Coagul Disord. 2010 Jul 1;2(2):19–27.

Figure 2. Schematic representation of FVIII, FVIIIa, and FVIII-SQ.

Figure 2

Schematic A1-A2-B-A3-C1-C2 domain representation of human FVIII and FVIIIa. The acidic regions denoted by a1, a2, and a3 are indicated in red, thrombin cleavage sites are indicated by green arrows, and yellow circles represent potential N-linked glycosylation sites.