TABLE 5.
Type 2 diabetes by median fish intake and potential mediation by eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA)1
| Quintiles of fish consumption | No. of cases | Full model | Full model + DHA | Full model + EPA |
| 1 (0.47 servings of fish/wk) | 464 | 1.0 | 1.0 | 1.0 |
| 2 (0.93 servings of fish/wk) | 450 | 1.11 (0.98,1.27)2 | 1.01 (0.86,1.18) | 1.08 (0.91,1.29) |
| 3 (1.47 servings of fish/wk) | 402 | 1.17 (1.02,1.34) | 1.02 (0.85,1.22) | 1.12 (0.90,1.38) |
| 4 (1.93 servings of fish/wk) | 503 | 1.35 (1.19,1.54) | 1.12 (0.92,1.38) | 1.28 (1.02,1.62) |
| 5 (3.93 servings of fish/wk) | 551 | 1.49 (1.30,1.70) | 1.19 (0.94,1.51) | 1.42 (1.11,1.80) |
| P for trend | — | <0.0001 | 0.10 | 0.002 |
1
Full model was adjusted for age, BMI, parental history of diabetes, smoking (never, former, or current), exercise (quintiles of metabolic equivalent task hours per week), alcohol intake (4 categories), menopausal status (not sure or pre- or postmenopausal), red-meat intake, and quintiles of energy intake, linoleic acid, α-linolenic acid, dietary magnesium, trans fat, saturated fat, cereal fiber, and glycemic index by using Cox proportional hazard models.
2
Hazard ratio; 95% CI in parentheses (all such values).