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. Author manuscript; available in PMC: 2011 Dec 15.
Published in final edited form as: Bioorg Med Chem Lett. 2010 Oct 21;20(24):7323–7326. doi: 10.1016/j.bmcl.2010.10.060

Figure 5. Cleavage of the Tetrazolium Salt WST-1.

Figure 5

(4-[3-(4-iodophenyl)-2-(4-nitrophenyl)-2H-5-tetrazolio]-1,3-benzene disulfonate): six potent analogs identified by scratch assay were evaluated for their ability to directly inhibit ECTO-NOX proteins by WST-1 assay at the indicated concentrations. Analog 4b exhibited significant ENOX inhibition at 10µM.